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research rounds
Subscribe to stay up to date with emerging research and hot topics within dermatology.
Breaking the Itch-Scratch Cycle in Prurigo Nodularis with IL-31 Blockade
Original Article : Phase 3 Trial of Nemolizumab in Patients with Prurigo Nodularis What are the key takeaways of this article? Prurigo nodularis (PN) is a chronic skin condition marked by severe, relentless itching and hard bumps caused by repeated scratching. Many patients describe it simply as “chronic itch” or are told they have “neurodermatitis.” PN is not the same as atopic dermatitis (eczema), although the two can overlap. In PN, itch is the central problem, often leadi
Nicole Chu
Mar 52 min read
Rethinking Acne: The Skin Barrier Perspective
Original Article : Skin Barrier Dysfunction in Acne Vulgaris: Pathogenesis and Therapeutic Approaches What are the key takeaways of this article? Acne vulgaris is one of the most common dermatologic conditions worldwide and its pathogenesis is traditionally described by four main processes: increased sebum production, follicular hyperkeratinization, bacterial colonization and proliferation within obstructed follicles, particularly by Cutibacterium acnes , and subsequent immun
Ella Liu
Jan 292 min read
Dermatology in the North: Barriers to Dermatological Care and Opportunity for Virtual Pathways in Northern and Rural Canadian Indigenous Communities
Original Article : Understanding Burdens and Barriers to Dermatological Management, and Potential for Virtual Care in Northern and Rural Canadian Indigenous Communities: A National Healthcare Practitioner Cross-Sectional Survey Analysis What are the key takeaways of this article? Northern and Rural Canadian Indigenous communities (NRCIC) face long-standing systemic inequities, mainly rooted in colonial history, geographic isolation, and limited local resources. These factors
April Foote
Dec 10, 20252 min read
Psychiatric Outcomes After Isotretinoin
Original Article : Risk of Suicide and Psychiatric Disorders Among Isotretinoin Users: A Meta-Analysis What are the key takeaways of this article? This large meta-analysis aimed to clarify whether isotretinoin, a widely used treatment for severe acne, is associated with increased risk of suicide or psychiatric disorders. The study synthesized data from 25 observational studies involving over 1.6 million participants, analyzing both the absolute and relative risks of psychiatr
Parsa Abdi
Nov 21, 20252 min read
MACE and VTE: Which Psoriasis Treatment is Safest?
Original Article : Risk of major adverse cardiovascular events and venous thromboembolic events between patients with psoriasis or psoriatic arthritis on tumor necrosis factor inhibitors, interleukin 17 inhibitors, interleukin 12/23 inhibitors, and interleukin 23 inhibitors: An emulated target trial analysis What are the key takeaways of this article? Psoriasis and psoriatic arthritis, collectively referred to as psoriatic disease, are chronic inflammatory conditions that n
Nicholas Chiang
Oct 30, 20252 min read
Targeting the Root: IFNβ Inhibition Shows Promise in Dermatomyositis
Original Article : Efficacy, safety, and target engagement of dazukibart, an IFNβ specific monoclonal antibody, in adults with...
Zili Zhou
Jul 22, 20252 min read
Should We Follow the Light? A Review of LED Devices in Acne Treatment
Original Article : At-Home LED Devices for the Treatment of Acne Vulgaris: A Systematic Review and Meta-Analysis What are the key...
Taylor Skinner
Jul 7, 20252 min read
Turning the Tide on Vitiligo: Can JAK Inhibitors and Phototherapy Paint a New Future?
Original Article : Combination of Baricitinib and Phototherapy in Adults With Active Vitiligo: A Randomized Clinical Trial What are the...
Adam Bai
Jun 30, 20252 min read
Restoring Immune Balance: Targeting SSAT to Treat Psoriasis and Chronic Inflammation
Original Article : The polyamine-regulating enzyme SSAT1 impairs tissue regulatory T cell function in chronic cutaneous inflammation What...
Miranda Branyiczky
May 24, 20252 min read
More Than Skin Deep: Measuring the Emotional Toll of Acne
Original Article : Development of the acne-specific quality of life questionnaire Quality of Life Relevance-Acne What are the key...
Megan Lowe
Apr 16, 20252 min read
Re-Framing The Safety of JAK Inhibitors: A Maximum-Use Trial of Topical Ruxolitinib in Children with Eczema
Original Article : A Maximum-Use Trial of Ruxolitinib Cream in Children Aged 2-11 Years with Moderate to Severe Atopic Dermatitis What...
Nicholas Chiang
Mar 21, 20253 min read
No Link Between Smoking and Eczema
Original Article : Atopic dermatitis and tobacco smoke exposure during childhood and adolescence What are the key takeaways of this...
Parsa Abdi
Feb 27, 20252 min read
Applications of High-Resolution Ultrasound in Dermatology
Original Article : Seeing beyond skin deep: High-resolution ultrasound in dermatology—A comprehensive review and future prospects What...
Zili Zhou
Feb 11, 20252 min read
Unveiling the Hidden Cost: Navigating Psoriasis Risk with Immune Checkpoint Inhibitors
Original Article : Psoriasis Risk With Immune Checkpoint Inhibitors What are the key takeaways of this article? A novel study by To et...
Adam Bai
Jan 26, 20252 min read
Upadacitinib: A Promising Long-Term Treatment for Teens with Moderate-to-Severe Eczema
Original Article : Upadacitinib in Adolescents With Moderate to Severe Atopic Dermatitis: Analysis of 3 Phase 3 Randomized Clinical...
Miranda Branyiczky
Jan 14, 20253 min read
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