Original Article : Skin Barrier Dysfunction in Acne Vulgaris: Pathogenesis and Therapeutic Approaches What are the key takeaways of this article? Acne vulgaris is one of the most common dermatologic conditions worldwide and its pathogenesis is traditionally described by four main processes: increased sebum production, follicular hyperkeratinization, bacterial colonization and proliferation within obstructed follicles, particularly by Cutibacterium acnes , and subsequent immune mediated...