Original Article : Upadacitinib for the Treatment of Pyoderma Gangrenosum: A Literature Review What are the key takeaways of this article? Pyoderma gangrenosum (PG) is a rare, noninfectious neutrophilic dermatosis characterized by painful nodules that rapidly progress to ulceration. It is often associated with systemic inflammatory conditions such as inflammatory bowel disease and rheumatoid arthritis, and can be difficult to treat due to its refractory nature. Increasing evidence suggests...